Research Article
Clinical Performance of an Ultrahigh Resolution Chromosomal Microarray Optimized for Neurodevelopmental Disorders
Table 5
Diagnostic yield by age in ID/DD (986 females and 2148 males, total
).
| | Age in years | Total tests | Pathogenic
(% yield) | VOUS
(% yield) | Normal (%) |
| | 0-1 | 95 | 16 (16.8%) | 15 (15.8%) | 64 (67.4%) | | 1–3.4 | 950 | 87 (9.2%) | 188 (19.8%) | 675 (71.1%) | | 3.5–5.4 | 572 | 54 (9.4%) | 103 (18.0%) | 415 (72.6%) | | 5.5–10.0 | 775 | 92 (11.9%) | 152 (19.6%) | 531 (68.5%) | | 10.1–18 | 623 | 65 (10.4%) | 117 (18.8%) | 441 (70.8%) | | 18+ | 119 | 20 (16.8%) | 26 (21.8%) | 73 (61.3%) | | Total | 3134 | 334 (10.7%) | 601 (19.2%) | 2199 (70.2%) |
|
|
