Research Article
Clinical Performance of an Ultrahigh Resolution Chromosomal Microarray Optimized for Neurodevelopmental Disorders
Table 7
Diagnostic yield by age in ASD (622 females and 2394 males, total
).
| | Age in years | Number of tests | Pathogenic
(% yield) | VOUS
(% yield) | Normal (%) |
| | 0–3.4 | 735 | 28 (3.8%) | 134 (18.2%) | 573 (78.0%) | | 3.5–5.4 | 688 | 33 (4.8%) | 121 (17.6%) | 534 (77.6%) | | 5.5–10 | 789 | 50 (6.3%) | 158 (20.0%) | 581 (73.6%) | | 10.1–18 | 679 | 59 (8.7%) | 138 (20.3%) | 482 (71.0%) | | 18+ | 125 | 8 (6.4%) | 25 (20%) | 92 (73.6%) | | Total | 3016 | 178 (5.9%) | 576 (19%) | 2262 (75%) |
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