Research Article
Clinical Performance of an Ultrahigh Resolution Chromosomal Microarray Optimized for Neurodevelopmental Disorders
Table 9
Diagnostic yield by age in neurodevelopmental disorders and/or MCA, excluding ASD (females = 909; males = 1486; total
).
| | Age in years | Total
(excluding ASD) | Pathogenic
(% yield) | VOUS
(% yield) | Normal (%) |
| | 0–1 | 204 | 38 (18.6%) | 37 (18.1%) | 129 (63.2%) | | 1–3.4 | 699 | 84 (12.0%) | 146 (20.9%) | 469 (67.1%) | | 3.5–5.4 | 344 | 43 (12.5%) | 63 (18.3%) | 238 (69.2%) | | 5.5–10 | 589 | 82 (13.9%) | 121 (20.5%) | 386 (65.5%) | | 10.1–18 | 461 | 55 (11.9%) | 83 (18.0%) | 323 (70.1%) | | 18+ | 98 | 19 (19.4%) | 15 (15.3%) | 64 (65.3%) | | Total | 2395 | 321 (13.4%) | 465 (19.4%) | 1609 (67.2%) |
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