iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine

Table 1

Clinical diagnosis of patients who participated in this study.

Diagnosis	Unit	LSSD-CHB ()	DHSM-CHB ()	HCTL ()	value
Sex
Male		24	15	10
Female		6	15	10
Age	Years	17~56	18~60	24~56
Mean age		30.8	36.83	36.15
Standard deviation (SD)		10.526	11.885	11.554
Hepatitis B surface antigen (HBsAg)
Positive		28	29
Negative		0	0
Hepatitis surface antibody (anti-HBs)
Positive		2	0
Negative		25	29
Hepatitis Be antigen (HBeAg)
Positive		21	19
Negative		7	9
Hepatitis Be antibody (anti-HBe)
Positive		9	12
Negative		19	16
Hepatitis B core antibody (anti-HBc)
Positive		28	29
Negative		0	0
Alanine transaminase (ALT)	IU/L	13.8~627	34~673		1.0
Mean ALT level		190.153	187.393
SD		161.231	177.618
Aspartate aminotransferase (AST)	IU/L	26.5~345	28~556		0.9999
Mean AST		96.74	142.427
SD		71.699	153.539
Serum total bilirubin (STB)	umol/L	10.1~48.63	6.5~109.5		1.0
Mean STB		19.208	20.643
SD		8.926	18.127
Conjugated bilirubin (CB)	umol/L	2.4~16.4	2.3~99.2		1.0
Mean CB		6.923	9.408
SD		3.542	17.208
Unconjugated bilirubin (UCB)	umol/L	6~34.13	3.3~29.3		1.0
Mean UCB		12.284	11.182
SD		5.951	4.921
HBV-DNA	IU/mL	+ 03~1.12	+ 04~9.40		0.0096
Mean HBV-DNA
SD