A Novel Homozygous p.L539F Mutation Identified in <i>PINK1</i> Gene in a Moroccan Patient with Parkinsonism

<div>Chromosomal microarray analysis, Sanger sequencing, and sequence alignment for<i> PINK1 </i>gene. (a) Allele difference plot of patient III.1 showing a ROH of 11.68 Mb at<i> PINK1 </i>gene locus. (b) Sanger sequencing of<i> PINK1 </i>exon 8 showing the p.L539F mutation at homozygous state and the wild type sequence in a normal individual. (c) Multiple sequences alignment for human<i> PINK1 </i>gene. Conservation of amino acid L at position 539 among various species is indicated by arrow.</div>

BioMed Research International

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Figure 2: A Novel Homozygous p.L539F Mutation Identified in <i>PINK1</i> Gene in a Moroccan Patient with Parkinsonism 

BioMed Research International

A Novel Homozygous p.L539F Mutation Identified in PINK1 Gene in a Moroccan Patient with Parkinsonism

Figure 2