Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 3518989, 10 pages
http://dx.doi.org/10.1155/2016/3518989
Research Article

Establishment of a Novel Simplified Surgical Model of Acute Liver Failure in the Cynomolgus Monkey

1Second Department of Hepatobiliary Surgery, Zhujiang Hospital, State Key Laboratory of Organ Failure Research, Co-Innovation Center for Organ Failure Research, Southern Medical University, Guangzhou 510280, China
2Institute of Regenerative Medicine, Zhujiang Hospital, Guangdong Provincial Research Center for Artificial Organ and Tissue Engineering, Southern Medical University, Guangzhou 510280, China

Received 29 September 2016; Revised 19 November 2016; Accepted 28 November 2016

Academic Editor: Hartmut Jaeschke

Copyright © 2016 Lei Cai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Akamatsu, Y. Sugawara, and N. Kokudo, “Acute liver failure and liver transplantation,” Intractable & Rare Diseases Research, vol. 2, no. 3, pp. 77–87, 2013. View at Google Scholar
  2. W. Bernal and J. Wendon, “Acute liver failure,” The New England Journal of Medicine, vol. 369, no. 26, pp. 2525–2534, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. M. C. Donnelly, P. C. Hayes, and K. J. Simpson, “The changing face of liver transplantation for acute liver failure: assessment of current status and implications for future practice,” Liver Transplantation, vol. 22, no. 4, pp. 527–535, 2016. View at Publisher · View at Google Scholar
  4. J. P. Vacanti and K. M. Kulig, “Liver cell therapy and tissue engineering for transplantation,” Seminars in Pediatric Surgery, vol. 23, no. 3, pp. 150–155, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Saliba and D. Samuel, “Artificial liver support: a real step forward,” Minerva Medica, vol. 106, no. 1, pp. 35–43, 2015. View at Google Scholar · View at Scopus
  6. X.-L. Shi, Y. Gao, Y. Yan et al., “Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes,” Cell Research, vol. 26, no. 2, pp. 206–216, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. K. C. L. Lee, L. A. Baker, G. Stanzani et al., “Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: results of a pivotal pre-clinical study,” Journal of Hepatology, vol. 63, no. 3, pp. 634–642, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Thiel, M. Schenk, A. Etspüler et al., “A simple dummy liver assist device prolongs anhepatic survival in a porcine model of total hepatectomy by slight hypothermia,” BMC Gastroenterology, vol. 11, article 79, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. M. J. Tuñón, M. Alvarez, J. M. Culebras, and J. González-Gallego, “An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure,” World Journal of Gastroenterology, vol. 15, no. 25, pp. 3086–3098, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Tsaroucha, C. Chondrogiannis, A. Mani, and C. Staikou, “Myocardial involvement during ischemia-induced acute liver failure in the pig,” Journal of Investigative Surgery, vol. 26, no. 2, pp. 99–104, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Al-Chalabi, E. Matevossian, A.-K. V. Thaden et al., “Evaluation of the Hepa Wash® treatment in pigs with acute liver failure,” BMC Gastroenterology, vol. 13, no. 1, article 83, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Sawara, P. Desjardins, N. Chatauret, A. Kato, K. Suzuki, and R. F. Butterworth, “Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure,” Neurochemistry International, vol. 55, no. 1–3, pp. 119–123, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. R. G. Kristiansen, C. F. Rose, O.-M. Fuskevåg et al., “L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 307, no. 10, pp. G1024–G1031, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. V. Sharma, G. A. M. ten Have, L. Ytrebo et al., “Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 303, no. 3, pp. G435–G441, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. Z. Chen and Y.-T. Ding, “Functional evaluation of a new bioartificial liver system in vivo and in vivo,” World Journal of Gastroenterology, vol. 12, no. 8, pp. 1312–1316, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. S. S. Awad, M. R. Hemmila, O. S. Soldes et al., “A novel stable reproducible model of hepatic failure in canines,” Journal of Surgical Research, vol. 94, no. 2, pp. 167–171, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. Z. Zhang, Y.-C. Zhao, Y. Cheng, G.-D. Jian, M.-X. Pan, and Y. Gao, “Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure,” World Journal of Gastroenterology, vol. 20, no. 46, pp. 17399–17406, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Maes, M. Vinken, and H. Jaeschke, “Experimental models of hepatotoxicity related to acute liver failure,” Toxicology and Applied Pharmacology, vol. 290, pp. 86–97, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. Z. Q. Qiu, L. Cai, and D. S. Chen, “Total flavonoids from mimosa pudica protects carbon tetrachloride-induced acute liver injury in mice,” Journal of International Translational Medicine, vol. 3, no. 1, pp. 6–10, 2015. View at Publisher · View at Google Scholar
  20. L. A. Baker, K. C. Lee, C. P. Jimenez et al., “Circulating microRNAs reveal time course of organ injury in a porcine model of acetaminophen-induced acute liver failure,” PLoS ONE, vol. 10, no. 5, Article ID e0128076, 2015. View at Publisher · View at Google Scholar
  21. K. C. L. Lee, C. P. Jimenez, H. Alibhai et al., “A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival,” Liver International, vol. 33, no. 4, pp. 544–551, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. J. M. Glorioso, S. A. Mao, B. Rodysill et al., “Pivotal preclinical trial of the spheroid reservoir bioartificial liver,” Journal of Hepatology, vol. 63, no. 2, pp. 388–398, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Zhou, J. Li, Y. Zhang et al., “Efficacy of coupled low-volume plasma exchange with plasma filtration adsorption in treating pigs with acute liver failure: a randomised study,” Journal of Hepatology, vol. 63, no. 2, pp. 378–387, 2015. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Prazak, E. Laszikova, T. Pantoflicek, O. Ryska, E. Koblihova, and M. Ryska, “Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigs,” BMC Gastroenterology, vol. 13, no. 1, article 98, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. O. Ryska, T. Pantoflicek, E. Laszikova, J. Prazak, E. Koblihova, and M. Ryska, “Artificial liver support system reduces intracranial pressure more effectively than bioartificial system: an experimental study,” International Journal of Artificial Organs, vol. 35, no. 7, pp. 503–510, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. N. Papoutsidakis, N. Arkadopoulos, V. Smyrniotis et al., “Early myocardial injury is an integral component of experimental acute liver failure—a study in two porcine models,” Archives of Medical Science, vol. 7, no. 2, pp. 217–223, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. O. Detry, Y. Gaspar, J.-P. Cheramy-Bien, P. Drion, M. Meurisse, and J.-O. Defraigne, “A modified surgical model of fulminant hepatic failure in the rat,” Journal of Surgical Research, vol. 181, no. 1, pp. 85–90, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. K. Knubben, C. Thiel, M. Schenk et al., “A new surgical model for hepatectomy in pigs,” European Surgical Research, vol. 40, no. 1, pp. 41–46, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Filipponi and F. Mosca, “Animal models of fulminant hepatic failure: need to test liver support devices,” Digestive and Liver Disease, vol. 33, no. 7, pp. 607–613, 2001. View at Publisher · View at Google Scholar · View at Scopus
  30. G. Defterevos, C. Nastos, A. Papalois et al., “Peritoneal albumin dialysis as a novel approach for liver support: study in a porcine model of acute hepatic failure,” Artificial Organs, vol. 40, no. 8, pp. 755–764, 2016. View at Publisher · View at Google Scholar
  31. R. G. Kristiansen, C. F. Rose, O.-M. Fuskevåg et al., “L-ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 307, no. 10, pp. G1024–G1031, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Benoist, R. Sarkis, M. Baudrimont et al., “A reversible model of acute hepatic failure by temporary hepatic ischemia in the pig,” Journal of Surgical Research, vol. 88, no. 2, pp. 63–69, 2000. View at Publisher · View at Google Scholar · View at Scopus
  33. G. H. de Groot, C. B. Reuvers, S. W. Schalm et al., “A reproducible model of acute hepatic failure by transient ischemia in the pig,” Journal of Surgical Research, vol. 42, no. 1, pp. 92–100, 1987. View at Publisher · View at Google Scholar · View at Scopus
  34. M.-P. van de Kerkhove, R. Hoekstra, T. M. van Gulik, and R. A. Chamuleau, “Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research,” Biomaterials, vol. 25, no. 9, pp. 1613–1625, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. Gao, N. Mu, X.-P. Xu, and Y. Wang, “Porcine acute liver failure model established by two-phase surgery and treated with hollow fiber bioartificial liver support system,” World Journal of Gastroenterology, vol. 11, no. 35, pp. 5468–5474, 2005. View at Publisher · View at Google Scholar · View at Scopus
  36. P. Zhou, J. Xia, G. Guo et al., “A Macaca mulatta model of fulminant hepatic failure,” World Journal of Gastroenterology, vol. 18, no. 5, pp. 435–444, 2012. View at Publisher · View at Google Scholar · View at Scopus