Complement Factor 3 Could Be an Independent Risk Factor for Mortality in Patients with HBV Related Acute-on-Chronic Liver Failure

Figure 3

Lower complement levels indicated liver injury in HBV-ACLF patients. A significant negative correlation was found between C3 levels and MELD-Na scores (a). C3, C4, and CH50 levels in serum were negatively correlated with serum Tbil levels (b) but positively associated with plasma PTA levels (c) in HBV-infected patients (chronic hepatitis B (CHB) and acute-on-chronic liver failure (ACLF)). There was a significant negative correlation between CH50 levels and HBV-DNA loads and a slight negative correlation between C3 levels and HBV-DNA loads in HBV-ACLF patients (d). Solid line, linear growth trend; , correlation coefficient. values were shown.

(a)

(b)

(c)

(d)