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BioMed Research International
Volume 2016 (2016), Article ID 3596415, 6 pages
http://dx.doi.org/10.1155/2016/3596415
Review Article

Cognitive Changes following Bilateral Deep Brain Stimulation of Subthalamic Nucleus in Parkinson’s Disease: A Meta-Analysis

1Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
2Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
3Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

Received 5 January 2016; Revised 21 March 2016; Accepted 27 April 2016

Academic Editor: Alfonso Fasano

Copyright © 2016 Yi Xie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary materials consisted of forest plots and funnel plots of meta-analysis results. Figures S1–S7 showed the difference of pretreatment age, disease duration, LED, UPDRS-III (medication-on), UPDRS-III (medication-off), Hoehn-Yahr (medication-on) and Hoehn-Yahr (medication-off) between DBS and control group. Figures S8, S10, S12, S14, S16, S18, S20, S22, S24, S26, S28, S30, S32 displayed the difference of cognitive scale score changes between DBS and control group. Publication bias of each comparison were visually examined through funnel plots of Figures S9, S11, S13, S15, S17, S19, S21, S23, S25, S27, S29, S31, S33.

  1. Supplementary Material