Research Article
Expression and Clinical Significance of the Novel Long Noncoding RNA ZNF674-AS1 in Human Hepatocellular Carcinoma
Table 1
Clinicopathological correlation of ZNF674-AS1 expression in human hepatocellular carcinoma (HCC). AFP: Alpha Fetal Protein; PVTT: Portal Vein Tumor Thrombus;
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| Parameters | Group | Total | ZNF674-AS1 expression | value | Low | High |
| Gender | Male | 118 | 85 | 33 | 0.88 | Female | 19 | 14 | 5 |
| Age | 60 | 88 | 64 | 24 | 0.87 | ≥60 | 49 | 35 | 14 |
| Hepatitis B | Absent | 40 | 31 | 9 | 0.61 | Present | 97 | 68 | 29 |
| Liver cirrhosis | Absent | 40 | 31 | 9 | 0.38 | Present | 97 | 68 | 29 |
| AFP | Negative | 51 | 36 | 15 | 0.74 | Positive | 86 | 63 | 23 |
| Tumor size | ≤3 | 27 | 20 | 7 | 0.82 | 3 | 110 | 79 | 31 |
| Tumor number | Single | 105 | 79 | 26 | 0.16 | Multiple | 32 | 20 | 12 |
| PVTT | Absent | 94 | 65 | 29 | 0.23 | Present | 43 | 34 | 9 |
| Metastasis | Absent | 121 | 84 | 37 | 0.0 | Present | 16 | 15 | 1 |
| Clinical stage | I-II | 102 | 69 | 33 | 0.03 | III-IV | 35 | 30 | 5 |
| Histopathologic grading | Poorly | 102 | 79 | 23 | 0.04 | Well + moderately | 35 | 20 | 15 |
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