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BioMed Research International
Volume 2016, Article ID 3620141, 5 pages
Research Article

Comparative Analysis of Human B Cell Epitopes Based on BCG Genomes

State Key Laboratory of Infectious Diseases Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

Received 22 March 2016; Accepted 16 May 2016

Academic Editor: Frederick D. Quinn

Copyright © 2016 Machao Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1: 15 genome sequences analyzed in this study. 15 strains used in this paper including 13 BCGs, 1 Mycobacterium tuberculosis and 1 Mycobacterium bovis.

Table S2: 399 B cell epitopes and coding genes. 81 genes encoding 399 verified B cell epitopes according the genomes of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis AF2122/97, respectively.

Table S3: Functional classification of genes coding B cell epitope. 81 genes which encoded B cell epitopes could be classified into 9 categories.

Table S4: B cell epitopes grouping in BCGs. All epitopes could be classified as 5 Groups based on distribution among BCGs.

  1. Supplementary Material