Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016 (2016), Article ID 3652068, 7 pages
http://dx.doi.org/10.1155/2016/3652068
Research Article

Increased Activity of the Intracardiac Oxytocinergic System in the Development of Postinfarction Heart Failure

1Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Sciences, Medical University of Warsaw, Warsaw, Poland
2Department of Cardiology, Hypertension, and Internal Medicine, 2nd Medical Faculty, Medical University of Warsaw, Warsaw, Poland
3Department of Immunology, Transplantology and Internal Diseases, Transplantation Institute, Medical University of Warsaw, Warsaw, Poland

Received 15 July 2016; Revised 8 October 2016; Accepted 18 October 2016

Academic Editor: Ji-Fu Wei

Copyright © 2016 Agnieszka Wsol et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Ivell and J. A. Russell, “Oxytocin: cellular and molecular approaches in medicine and research,” Reviews of Reproduction, vol. 1, pp. 13–18, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. A.-M. Bao, G. Meynen, and D. F. Swaab, “The stress system in depression and neurodegeneration: focus on the human hypothalamus,” Brain Research Reviews, vol. 57, no. 2, pp. 531–553, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. I. D. Neumann and R. Landgraf, “Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors,” Trends in Neurosciences, vol. 35, no. 11, pp. 649–659, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. D. M. Cochran, D. Fallon, M. Hill, and J. A. Frazier, “The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings,” Harvard Review of Psychiatry, vol. 21, no. 5, pp. 219–247, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Anagnostou, L. Soorya, J. Brian et al., “Intranasal oxytocin in the treatment of autism spectrum disorders: a review of literature and early safety and efficacy data in youth,” Brain Research, vol. 1580, pp. 188–198, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Barberis and E. Tribollet, “Vasopressin and oxytocin receptors in the central nervous system,” Critical Reviews in Neurobiology, vol. 10, no. 1, pp. 119–154, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. M. L. Boccia, P. Petrusz, K. Suzuki, L. Marson, and C. A. Pedersen, “Immunohistochemical localization of oxytocin receptors in human brain,” Neuroscience, vol. 253, pp. 155–164, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. J. B. Sartain, J. J. Barry, P. W. Howat, D. I. McCormack, and M. Bryant, “Intravenous oxytocin bolus of 2 units is superior to 5 units during elective Caesarean section,” British Journal of Anaesthesia, vol. 101, no. 6, pp. 822–826, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Wsł, A. Cudnoch-Jedrzejewska, E. Szczepanska-Sadowska, S. Kowalewski, and J. Dobruch, “Central oxytocin modulation of acute stress-induced cardiovascular responses after myocardial infarction in the rat,” Stress, vol. 12, no. 6, pp. 517–525, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Gutkowska, Y. Aliou, J. L. Lavoie, K. Gaab, M. Jankowski, and T. L. Broderick, “Oxytocin decreases diurnal and nocturnal arterial blood pressure in the conscious unrestrained spontaneously hypertensive rat,” Pathophysiology, vol. 23, no. 2, pp. 111–121, 2016. View at Publisher · View at Google Scholar
  11. M. Petersson and K. Uvnäs-Moberg, “Effects of an acute stressor on blood pressure and heart rate in rats pretreated with intracerebroventricular oxytocin injections,” Psychoneuroendocrinology, vol. 32, no. 8–10, pp. 959–965, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Wsol, E. Szczepanska-Sadowska, S. Kowalewski, L. Puchalska, and A. Cudnoch-Jedrzejewska, “Oxytocin differently regulates pressor responses to stress in WKY and SHR rats: the role of central oxytocin and V1a receptors,” Stress, vol. 17, no. 1, pp. 117–125, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Jankowski, F. Hajjar, S. Al Kawas et al., “Rat heart: a site of oxytocin production and action,” Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 24, pp. 14558–14563, 1998. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Jankowski, D. Wang, F. Hajjar, S. Mukaddam-Daher, S. M. McCann, and J. Gutkowska, “Oxytocin and its receptors are synthesized in the rat vasculature,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 11, pp. 6207–6211, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Gutkowska, M. Jankowski, C. Lambert, S. Mukaddam-Daher, H. H. Zingg, and S. M. McCann, “Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart,” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 21, pp. 11704–11709, 1997. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. Alizadeh, M. Faghihi, H. R. Sadeghipour, F. MohammadGhasemi, and V. Khori, “Role of endogenous oxytocin in cardiac ischemic preconditioning,” Regulatory Peptides, vol. 167, no. 1, pp. 86–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Jankowski, V. Bissonauth, L. Gao et al., “Anti-inflammatory effect of oxytocin in rat myocardial infarction,” Basic Research in Cardiology, vol. 105, no. 2, pp. 205–218, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Faghihi, A. M. Alizadeh, V. Khori, M. Latifpour, and S. Khodayari, “The role of nitric oxide, reactive oxygen species, and protein kinase C in oxytocin-induced cardioprotection in ischemic rat heart,” Peptides, vol. 37, no. 2, pp. 314–319, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Ondrejcakova, T. Ravingerova, J. Bakos, D. Pancza, and D. Jezova, “Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusion,” Canadian Journal of Physiology and Pharmacology, vol. 87, no. 2, pp. 137–142, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Dobruch, A. Cudnoch-Jedrzejewska, and E. Szczepanska-Sadowska, “Enhanced involvement of brain vasopressin V1 receptors in cardiovascular responses to stress in rats with myocardial infarction,” Stress, vol. 8, no. 4, pp. 273–284, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. F. H. H. Leenen, B. Yuan, and B. S. Huang, “Brain ‘ouabain’ and angiotensin II contribute to cardiac dysfunction after myocardial infarction,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 277, no. 5, pp. H1786–H1792, 1999. View at Google Scholar · View at Scopus
  22. A. Cudnoch-Jedrzejewska, E. Szczepanska-Sadowska, J. Dobruch et al., “Differential sensitisation to central cardiovascular effects of angiotensin II in rats with a myocardial infarct: relevance to stress and interaction with vasopressin,” Stress, vol. 11, no. 4, pp. 290–301, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. R. Ghashghaei, B. Arbit, and A. S. Maisel, “Current and novel biomarkers in heart failure: bench to bedside,” Current Opinion in Cardiology, vol. 31, no. 2, pp. 191–195, 2016. View at Publisher · View at Google Scholar · View at Scopus
  24. M. A. Haanwinckel, L. K. Elias, A. L. V. Favaretto, J. Gutkowska, S. M. Mccann, and J. Antunes-Rodrigues, “Oxytocin mediates atrial natriuretic peptide release and natriuresis after volume expansion in the rat,” Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 17, pp. 7902–7906, 1995. View at Publisher · View at Google Scholar · View at Scopus
  25. T. J. Soares, T. M. Coimbra, A. R. Martins et al., “Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP,” Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 1, pp. 278–283, 1999. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Ondrejcakova, M. Barancik, M. Bartekova, T. Ravingerova, and D. Jezova, “Prolonged oxytocin treatment in rats affects intracellular signaling and induces myocardial protection against infarction,” General Physiology and Biophysics, vol. 31, no. 3, pp. 261–270, 2012. View at Google Scholar
  27. A. Gonzalez-Reyes, A. Menaouar, D. Yip et al., “Molecular mechanisms underlying oxytocin-induced cardiomyocyte protection from simulated ischemia-reperfusion,” Molecular and Cellular Endocrinology, vol. 412, pp. 170–181, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. G. Gimpl, K. Burger, E. Politowska, J. Ciarkowski, and F. Fahrenholz, “Oxytocin receptors and cholesterol: interaction and regulation,” Experimental Physiology, vol. 85, pp. 41S–49S, 2000. View at Google Scholar · View at Scopus
  29. G. Gimpl and F. Fahrenholz, “The oxytocin receptor system: structure, function, and regulation,” Physiological Reviews, vol. 81, no. 2, pp. 629–683, 2001. View at Google Scholar
  30. S. Phaneuf, G. Asbóth, M. P. Carrasco et al., “The desensitization of oxytocin receptors in human myometrial cells is accompanied by down-regulation of oxytocin receptor messenger RNA,” Journal of Endocrinology, vol. 154, no. 1, pp. 7–18, 1997. View at Publisher · View at Google Scholar · View at Scopus
  31. B. F. Mitchell and R. Chibbar, “Synthesis and metabolism of oxytocin in late gestation in human decidua,” Advances in Experimental Medicine and Biology, vol. 395, pp. 365–380, 1995. View at Google Scholar
  32. L. J. Young, S. Muns, Z. Wang, and T. R. Insel, “Changes in oxytocin receptor mRNA in rat brain during pregnancy and the effects of estrogen and interleukin-6,” Journal of Neuroendocrinology, vol. 9, no. 11, pp. 859–865, 1997. View at Google Scholar · View at Scopus
  33. M. A. Cavasin, S. S. Sankey, A.-L. Yu, S. Menon, and X.-P. Yang, “Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 284, no. 5, pp. H1560–H1569, 2003. View at Publisher · View at Google Scholar · View at Scopus