Review Article

Microbial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer Treatment

Figure 3

Pladienolide analogs. (a) General structure of Pladienolides A–G, which was determined by 1H, 13C NMR, MS, IR, and 2D NMR analyses. Radicals for each isoform are summarized in the table. (b) Different functional analogs have also been reported.
(a)
(b)