Iontophoresis-Assisted Corneal Collagen Cross-Linking with Epithelial Debridement: Preliminary Results
Table 1
Clinical outcome of standard corneal collagen cross-linking using iontophoresis (I-SCXL).
Outcome
Baseline
One month
Three months
Six months
BSCVA
0.69 0.17
0.73 0.18
0.33
0.81 0.21
0.01
0.82 0.17
0.002
Sphere
−1.13 2.04
−0.37 2.06
0.04
−0.86 1.67
0.6
−0.54 1.49
0.1
Cylinder
−3.25 1.26
−3.76 1.62
0.1
−3.51 1.66
0.4
−2.90 1.36
0.1
AX
105 36.24
107.5 29.49
0.8
95.5 34.9
0.3
110.3 26.57
0.5
53.63 5.60
53.67 6.38
0.9
53.51 5.63
1
51.9 4.89
0.3
SAI
6.17 3.65
6.91 3.63
0.06
6.47 3.43
0.3
4.26 3.50
0.1
SI
7.35 2.83
7.45 2.88
0.3
7.36 2.98
0.9
6.95 2.85
0.02
ISV
84.35 29.75
91.2 32.9
0.06
87.5 31.47
0.2
79.88 33.32
0.8
IVA
0.98 0.39
1.05 0.45
0.1
0.93 0.37
0.6
0.93 0.42
0.7
KI
1.21 0.08
1.23 0.99
0.004
1.22 0.09
0.1
1.20 0.09
0.5
CKI
1.03 0.05
1.05 0.05
0.01
1.04 0.05
0.4
1.02 0.04
0.6
IHA
31.62 27.54
26.39 22.25
0.3
29.51 20.09
0.6
21.3 13.54
0.1
IHD
0.08 0.03
0.08 0.03
0.5
0.08 0.03
0.8
0.10 0.11
0.3
6.36 0.62
6.30 0.77
0.4
6.36 0.65
0.1
6.45 0.65
0.2
ThCT
473.6 36.50
441.8 41.72
<0.001
441.35 49.32
<0.001
452.7 53.10
0.0002
HOA
0.32 0.15
0.36 0.15
0.008
0.31 0.13
0.57
0.30 0.13
0.85
COMA
0.51 0.33
0.64 0.37
0.0002
0.56 0.36
0.09
0.46 0.32
0.89
Absph
−0.03 0.06
0.007 0.08
0.02
−0.013 0.08
0.1
−0.03 0.07
0.64
BSCVA: best spectacle corrected visual acuity; sphere: sphere refraction; cylinder: cylinder; AX: axis of the cylinder; : maximum keratometry; SAI: surface asymmetry index; SI: symmetry index; ISV: index of surface variance; IVA: index of vertical asymmetry; KI: keratoconus index; CKI: central keratoconus index; IHA: index of height asymmetry; IHD: index of height decentration; : minimum radius of curvature; ThCT: minimum pachymetry; HOA: high-order aberration; COMA: comatic aberration; Absph: spherical aberration.