Clinical Study

Iontophoresis-Assisted Corneal Collagen Cross-Linking with Epithelial Debridement: Preliminary Results

Table 1

Clinical outcome of standard corneal collagen cross-linking using iontophoresis (I-SCXL).

OutcomeBaselineOne monthThree monthsSix months

BSCVA0.69 0.170.73 0.180.330.81 0.210.010.82 0.170.002
Sphere−1.13 2.04−0.37 2.060.04−0.86 1.670.6−0.54 1.490.1
Cylinder−3.25 1.26−3.76 1.620.1−3.51 1.660.4−2.90 1.360.1
AX105 36.24107.5 29.490.895.5 34.90.3110.3 26.570.5
53.63 5.6053.67 6.380.953.51 5.63151.9 4.890.3
SAI6.17 3.656.91 3.630.066.47 3.430.34.26 3.500.1
SI7.35 2.837.45 2.880.37.36 2.980.96.95 2.850.02
ISV84.35 29.7591.2 32.90.0687.5 31.470.279.88 33.320.8
IVA0.98 0.391.05 0.450.10.93 0.370.60.93 0.420.7
KI1.21 0.081.23 0.990.0041.22 0.090.11.20 0.090.5
CKI1.03 0.051.05 0.050.011.04 0.050.41.02 0.040.6
IHA31.62 27.5426.39 22.250.329.51 20.090.621.3 13.540.1
IHD0.08 0.030.08 0.030.50.08 0.030.80.10 0.110.3
6.36 0.626.30 0.770.46.36 0.650.16.45 0.650.2
ThCT473.6 36.50441.8 41.72<0.001441.35 49.32<0.001452.7 53.100.0002
HOA0.32 0.150.36 0.150.0080.31 0.130.570.30 0.130.85
COMA0.51 0.330.64 0.370.00020.56 0.360.090.46 0.320.89
Absph−0.03 0.060.007 0.080.02−0.013 0.080.1−0.03 0.070.64

BSCVA: best spectacle corrected visual acuity; sphere: sphere refraction; cylinder: cylinder; AX: axis of the cylinder; : maximum keratometry; SAI: surface asymmetry index; SI: symmetry index; ISV: index of surface variance; IVA: index of vertical asymmetry; KI: keratoconus index; CKI: central keratoconus index; IHA: index of height asymmetry; IHD: index of height decentration; : minimum radius of curvature; ThCT: minimum pachymetry; HOA: high-order aberration; COMA: comatic aberration; Absph: spherical aberration.