A Rapid In-Clinic Test Detects Acute Leptospirosis in Dogs with High Sensitivity and Specificity

Table 2

MAT versus WITNESS Lepto: 2 × 2 table of weighted and unweighted results used for the calculation of sensitivity and specificity.

(a) Unweighted results

WITNESS Lepto	⁢MAT positive ()	⁢MAT negative ()
Positive	TP: 49 (positive group)	FP: 10 (borderline group)
Negative	FN: 1 (positive group)	TN: 25 (borderline group),
		50 (negative group)

(b) Weighted data used to calculate Se and Sp

WITNESS Lepto	⁢MAT positive ()	⁢MAT negative ()
Positive	TP: 33.075	FP: 6.55
Negative	FN: 0.675	TN: 94.45
	Sensitivity: 98%	Specificity: 93.5%

MAT: microscopic agglutination test; Se: sensitivity; Sp: specificity; TP: true positive; TN: true negative; FP: false positive; FN: false negative.