Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

Scheme 1

Reagents and conditions: (a) Zn, AcOH, reflux [15]; (b) HCl, EtOH-H₂O, 25°C [15]; (c) SOCl₂, DMF, reflux [15]; (d) AcCl, NEt₃, CH₂Cl₂, reflux [16]; (e) DMF, (CH₃)₂RN, 50°C; (f) H₂O, HCl, 25°C.