Research Article
Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives
Table 1
In vitro antimicrobial activity of the obtained 4-deoxypyridoxine ammonium salts.
| | Compounds | MICs (µg/mL) | | Gram-positive bacteria | Gram-negative bacteria | | S. aureus | S. epidermidis | M. luteus | E. coli K12 | S. typhimurium TA100 | P. aeruginosa |
| | 4a | >64 | >64 | >64 | >64 | >64 | >64 | | 4b | >64 | 32 | >64 | >64 | >64 | >64 | | 4c | 32 | 2 | 4 | 4 | 8 | >64 | | 5a | >64 | >64 | >64 | >64 | >64 | >64 | | 5b | >64 | >64 | >64 | >64 | >64 | >64 | | 5c | 8 | 4 | 8 | 2 | 16 | >64 | | Miramistin | 4 | 2 | 2 | 32 | >64 | 16 | | Benzalkonium chloride | 2 | 2 | 32 | 4 | 16 | 64 |
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