Research Article

Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

Table 4

DNA-damage activity of 4c and 5c in the SOS-chromotest (ratio, fold increase over the solvent control).

CompoundsConcentration, μg/mL
42040

4c0.9 0.321.3 0.251.4 0.45
5c1.2 0.351.5 0.431.3 0.53
Mitomycin C11.7 2.5