Clinical Study
Transcatheter Mitral Valve Repair in Surgical High-Risk Patients: Gender-Specific Acute and Long-Term Outcomes
Table 4
Postprocedural outcome, echocardiographic variables.
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| Baseline | Discharge | 12 months | 24 months | | | Men () | Women () | value | Men () | Women () | value | Men () | Women () | value | Men () | Women () | value |
| | MR severity No. (%) | | | 0.16 | | | 0.21 | | | 0.77 | | | 0.21 | | 0 | 0 | 0 | — | 0 | 0 | — | 1 (1) | 1 (1.6) | 1.00 | 1 (1.3) | 1 (1.9) | 1.00 | | 1 | 0 | 0 | — | 177 (49.9) | 94 (41.0) | 0.046 | 31 (30.7) | 15 (24.2) | 0.47 | 26 (34.2) | 12 (23.1) | 0.25 | | 2 | 0 | 0 | — | 140 (39.4) | 107 (46.7) | 0.098 | 60 (59.4) | 37 (59.7) | 1.00 | 43 (56.6) | 29 (55.8) | 1.00 | | 3 | 187 (51.7) | 111 (43.3) | 0.47 | 23 (6.5) | 18 (7.9) | 0.64 | 8 (7.9) | 8 (12.9) | 0.44 | 6 (7.9) | 10 (19.2) | 0.10 | | 4 | 175 (48.3) | 117 (50.9) | 0.61 | 8 (2.3) | 3 (1.3) | 0.61 | 1 (1) | 1 (1.6) | 1.00 | 0 | 0 | — | | Total stroke volume (mL) | 69.0 (53.7–87.4) | 60.2 (46.1–75.0) | <0.001 | 64.0 (54.0–78.4) | 55.0 (47.2–65.8) | <0.001 | 67.1 (55.3–84.0) | 65.3 (56.9–69.1) | 0.20 | 68.8 (55.7–80.7) | 57.1 (46.4–75.9) | 0.11 | | Forward stroke volume (mL) | 40.8 (31.2–52.0) | 37.3 (29.5–45.4) | 0.0023 | 52.0 (41.6–62.4) | 45.4 (37.3–53.2) | <0.001 | 54.3 (43.7–66.0) | 53.2 (43.7–58.9) | 0.36 | 58.0 (48.0–68.7) | 51.6 (38.0–61.2) | 0.026 | | Regurgitant fraction (%) | 42.5 (31.6–53.2) | 38.7 (27.1–48.2) | 0.016 | 18.0 (9.2–27.1) | 18.0 (10.0–28.7) | 0.59 | 19.3 (13.8–26.3) | 19.4 (10.1–27.5) | 0.23 | 16.2 (9.4–24.4) | 24.1 (10.5–30.8) | 0.078 | | Regurgitant volume (mL) | 29.3 (18.7–43.9) | 23.7 (13.1–36.0) | <0.001 | 11.3 (4.8–17.4) | 9.6 (5.2–17.5) | 0.54 | 13.5 (9.0–20.3) | 11.7 (6.0–18.2) | 0.12 | 10.1 (6.2–18.5) | 12.7 (3.6–20.4) | 0.45 | | Mitral valve orifice area (cm2) | 3.8 (3.2–4.6) | 3.7 (3.1–4.6) | 0.90 | 2.9 (2.5–3.4) | 2.9 (2.4–3.5) | 0.77 | 3.0 (2.3–3.8) | 2.8 (2.3–3.5) | 0.69 | 3.0 (2.2–3.6) | 2.8 (2.4–3.2) | 0.35 | | LV end-systolic volume (mL) | 113.8 (72.6–192.0) | 63.4 (44.6–102.8) | <0.001 | 126.0 (78.4–201.3) | 64.8 (41.8–128.1) | <0.001 | 113.3 (70.5–188.6) | 66.8 (48.4–112.1) | <0.001 | 133.3 (92.2–184.3) | 62.6 (48.1–115.0) | <0.001 | | LV end-systolic diameter (mm) | 53.0 (45.0–63.0) | 42.0 (36.0–52.6) | <0.001 | 56.0 (46.0–63.0) | 46.0 (37.0–54.6) | <0.001 | 52.5 (43.0–62.6) | 44.5 (35.8–54.6) | 0.0013 | 54.0 (45.7–63.3) | 45.0 (38.0–56.8) | 0.010 | | LV end-diastolic volume (mL) | 184.5 (139.4–259.9) | 124.8 (95.7–169.0) | <0.001 | 190.0 (151.4–265.4) | 131.2 (96.2–178.3) | <0.001 | 197.0 (145.8–245.0) | 141.6 (117.5–175.8) | <0.001 | 202.0 (163.5–261.9) | 140.4 (110.7–186.3) | <0.001 | | LV end-diastolic diameter (mm) | 66.0 (59.0–74.0) | 58.0 (51.0–64.0) | <0.001 | 66.5 (60.0–74.0) | 57.5 (52.0–66.0) | <0.001 | 65.0 (57.9–72.2) | 59.5 (54.0–67.0) | 0.013 | 65.0 (60.0–73.6) | 59.5 (54.9–67.0) | 0.0026 | | LV ejection fraction (%) | 39.0 ± 15.3 | 46.5 ± 15.1 | <0.001 | 35.7 ± 14.4 | 44.2 ± 15.5 | <0.001 | 38.9 ± 15.8 | 46.4 ± 15.0 | 0.0092 | 34.8 ± 11.8 | 45.6 ± 16.2 | <0.001 |
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LV = left ventricular; MR = mitral regurgitation.
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