Transcatheter Mitral Valve Repair in Surgical High-Risk Patients: Gender-Specific Acute and Long-Term Outcomes

Table 5

Univariate cox regression analysis for future death.

Variable	Men HR (95% CI)	value	Women HR (95% CI)	value
Age	1.02 (1.00–1.04)	0.0222	1.01 (0.99–1.04)	0.28
Body mass index	0.95 (0.91–1.00)	0.0289	0.98 (0.93–1.03)	0.39
Hypertension	0.97 (0.68–1.37)	0.86	1.04 (0.63–1.71)	0.89
Hypercholesterolemia	0.62 (0.45–0.85)	0.0031	1.02 (0.65–1.61)	0.94
Diabetes mellitus	1.03 (0.74–1.42)	0.87	1.78 (1.10–2.87)	0.019
Nicotine abuse	1.16 (0.78–1.72)	0.46	2.04 (1.17–3.53)	0.0115
Dilative cardiomyopathy	1.26 (0.88–1.78)	0.20	1.50 (0.94–2.39)	0.09
Ischemic cardiomyopathy	0.84 (0.62–1.15)	0.29	1.46 (0.92–2.34)	0.11
Coronary artery disease	0.66 (0.46–0.93)	0.0186	1.40 (0.90–2.19)	0.14
Renal failure	1.79 (1.27–2.52)	0.0009	1.97 (1.26–3.09)	0.0029
Atrial fibrillation	1.25 (0.89–1.75)	0.19	1.41 (0.87–2.29)	0.16
MR severity 4 versus 3	1.40 (1.02–1.91)	0.0355	1.23 (0.79–1.91)	0.36
LV ejection fraction < 30%	1.35 (0.97–1.90)	0.08	1.65 (0.94–2.90)	0.08
NT-proBNP (log)	1.43 (1.22–1.68)	<0.0001	1.93 (1.48–2.50)	<0.0001
Success rate	0.56 (0.35–0.90)	0.0172	0.78 (0.39–1.57)	0.49
Logistic EuroSCORE	1.00 (1.00–1.00)	0.83	1.02 (1.01–1.03)	0.0004
Peripheral artery disease	1.56 (0.97–2.50)	0.06	1.38 (0.67–2.88)	0.38

LV = left ventricular; MR = mitral regurgitation; NT-proBNP = N-terminal probrain natriuretic peptide; CI = confidence interval; HR = hazard ratio.