Transcatheter Mitral Valve Repair in Surgical High-Risk Patients: Gender-Specific Acute and Long-Term Outcomes

Table 6

Univariate cox regression analysis for future rehospitalization for heart failure.

Variable	Men HR (95% CI)	value	Women HR (95% CI)	value
Age	0.99 (0.97–1.01)	0.43	1.01 (0.98–1.03)	0.70
Body mass index	1.00 (0.96–1.05)	0.87	1.00 (0.95–1.06)	0.87
Hypertension	0.62 (0.41–0.94)	0.0226	1.69 (0.88–3.25)	0.12
Hypercholesterolemia	1.10 (0.74–1.63)	0.65	1.60 (0.96–2.67)	0.07
Diabetes mellitus	1.07 (0.71–1.61)	0.75	1.77 (0.99–3.15)	0.053
Nicotine abuse	1.50 (0.92–2.45)	0.11	0.98 (0.44–2.15)	0.96
Dilative cardiomyopathy	1.21 (0.76–1.90)	0.42	1.68 (0.98–2.87)	0.06
Ischemic cardiomyopathy	1.07 (0.72–1.60)	0.73	1.47 (0.85–2.54)	0.17
Coronary artery disease	0.91 (0.57–1.45)	0.70	1.06 (0.64–1.78)	0.82
Renal failure	1.32 (0.88–1.98)	0.18	0.75 (0.44–1.27)	0.29
Atrial fibrillation	1.13 (0.75–1.71)	0.56	1.03 (0.61–1.75)	0.91
MR severity 4 versus 3	0.90 (0.60–1.33)	0.58	1.45 (0.87–2.43)	0.15
LV ejection fraction <30%	1.89 (1.25–2.86)	0.0025	1.13 (0.56–2.25)	0.74
NT-proBNP (log)	1.29 (1.06–1.58)	0.0115	1.20 (0.90–1.58)	0.21
Success rate	0.46 (0.26–0.83)	0.0103	0.87 (0.38–2.03)	0.76
Logistic EuroSCORE	1.00 (1.00–1.00)	0.78	1.02 (1.01–1.03)	0.0055
Peripheral artery disease	1.08 (0.54–2.15)	0.82	1.12 (0.45–2.80)	0.81

LV = left ventricular; MR = mitral regurgitation; MV = mitral valve; NT-proBNP = N-terminal probrain natriuretic peptide; CI = confidence interval; HR = hazard ratio.