Docosahexaenoic Acid Rescues Synaptogenesis Impairment and Long-Term Memory Deficits Caused by Postnatal Multiple Sevoflurane Exposures

Figure 1

Multiple sevoflurane exposures decreased PSD95 and synaptophysin expressions in the hippocampus. (a) After multiple sevoflurane treatment, PSD95 and β-actin expressions in the hippocampus were detected by Western blot analysis. (b) The expressions of synaptophysin and β-actin were also determined after anesthesia. (c) The histogram shows PSD95/β-actin ratio in (a). (d) The histogram shows synaptophysin/β-actin ratio in (b). All data are presented as mean ± SEM; and comparing with control group, for each group. Sevo = sevoflurane.

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