Docosahexaenoic Acid Rescues Synaptogenesis Impairment and Long-Term Memory Deficits Caused by Postnatal Multiple Sevoflurane Exposures

Figure 4

DHA pretreatment improved spatial memory performance in the adulthood. (a) The escape latency of control + saline group, Sevo + saline group, Sevo + DHA group, and control + DHA group in the place trials of MWM was recorded in the seven successive days. (b) The platform crossing times in control + saline group, Sevo + saline group, Sevo + DHA group, and control + DHA group were shown. The data in (a) are presented as mean ± SEM. The data in (b) are shown as median and 95% confidence interval. , , and comparing with control group or sevoflurane group, in each group. MWM = Morris water maze. Sevo = sevoflurane. NS = no significance.

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