BioMed Research International
Volume 2016 (2016), Article ID 4062579, 7 pages
http://dx.doi.org/10.1155/2016/4062579
Research Article
Docosahexaenoic Acid Rescues Synaptogenesis Impairment and Long-Term Memory Deficits Caused by Postnatal Multiple Sevoflurane Exposures
1Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
2Department of Anesthesiology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Received 5 March 2016; Revised 7 July 2016; Accepted 12 July 2016
Academic Editor: Paula I. Moreira
Copyright © 2016 Guorong Tao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- R. T. Wilder, R. P. Flick, J. Sprung et al., “Early exposure to anesthesia and learning disabilities in a population-based birth cohort,” Anesthesiology, vol. 110, no. 4, pp. 796–804, 2009. View at Publisher · View at Google Scholar · View at Scopus
- R. P. Flick, S. K. Katusic, R. C. Colligan et al., “Cognitive and behavioral outcomes after early exposure to anesthesia and surgery,” Pediatrics, vol. 128, no. 5, pp. e1053–e1061, 2011. View at Publisher · View at Google Scholar · View at Scopus
- C. E. Creeley, K. T. Dikranian, G. A. Dissen, S. A. Back, J. W. Olney, and A. M. Brambrink, “Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain,” Anesthesiology, vol. 120, no. 3, pp. 626–638, 2014. View at Publisher · View at Google Scholar · View at Scopus
- T. M. Ramage, F. L. Chang, J. Shih et al., “Distinct long-term neurocognitive outcomes after equipotent sevoflurane or isoflurane anaesthesia in immature rats,” British Journal of Anaesthesia, vol. 110, supplement 1, pp. i39–i46, 2013. View at Publisher · View at Google Scholar · View at Scopus
- X. Shen, Y. Dong, Z. Xu et al., “Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment,” Anesthesiology, vol. 118, no. 3, pp. 502–515, 2013. View at Publisher · View at Google Scholar · View at Scopus
- G. Li, Q. Xue, Y. Luo, X. Hu, and B. Yu, “S6 inhibition contributes to isoflurane neurotoxicity in the developing brain,” Toxicology Letters, vol. 233, no. 2, pp. 102–113, 2015. View at Publisher · View at Google Scholar
- R. E. Martin and N. G. Bazan, “Changing fatty acid content of growth cone lipids prior to synaptogenesis,” Journal of Neurochemistry, vol. 59, no. 1, pp. 318–325, 1992. View at Publisher · View at Google Scholar · View at Scopus
- S. M. Innis, “Dietary omega 3 fatty acids and the developing brain,” Brain Research, vol. 1237, pp. 35–43, 2008. View at Publisher · View at Google Scholar · View at Scopus
- C. He, X. Qu, L. Cui, J. Wang, and J. X. Kang, “Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid,” Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 27, pp. 11370–11375, 2009. View at Publisher · View at Google Scholar · View at Scopus
- Y. Lin, M. Xu, J. Wan et al., “Docosahexaenoic acid attenuates hyperglycemia-enhanced hemorrhagic transformation after transient focal cerebral ischemia in rats,” Neuroscience, vol. 301, pp. 471–479, 2015. View at Publisher · View at Google Scholar · View at Scopus
- G. Tao, J. Zhang, L. Zhang et al., “Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice,” Anesthesiology, vol. 121, no. 3, pp. 510–527, 2014. View at Publisher · View at Google Scholar · View at Scopus
- J. Zhang, Y. Dong, C. Zhou, Y. Zhang, and Z. Xie, “Anesthetic sevoflurane reduces levels of hippocalcin and postsynaptic density protein 95,” Molecular Neurobiology, vol. 51, no. 3, pp. 853–863, 2015. View at Publisher · View at Google Scholar · View at Scopus
- E. Yavin, A. Brand, and P. Green, “Docosahexaenoic acid abundance in the brain: a biodevice to combat oxidative stress,” Nutritional Neuroscience, vol. 5, no. 3, pp. 149–157, 2002. View at Publisher · View at Google Scholar · View at Scopus
- D. Cao, K. Kevala, J. Kim et al., “Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function,” Journal of Neurochemistry, vol. 111, no. 2, pp. 510–521, 2009. View at Publisher · View at Google Scholar · View at Scopus
- A. Ahmad, T. Moriguchi, and N. Salem Jr., “Decrease in neuron size in docosahexaenoic acid-deficient brain,” Pediatric Neurology, vol. 26, no. 3, pp. 210–218, 2002. View at Publisher · View at Google Scholar · View at Scopus
- S. Yoshida, A. Yasuda, H. Kawazato et al., “Synaptic vesicle ultrastructural changes in the rat hippocampus induced by a combination of α-linolenate deficiency and a learning task,” Journal of Neurochemistry, vol. 68, no. 3, pp. 1261–1268, 1997. View at Google Scholar · View at Scopus
- W. Zhang, J. Liu, X. Hu et al., “N-3 polyunsaturated fatty acids reduce neonatal hypoxic/ischemic brain injury by promoting phosphatidylserine formation and akt signaling,” Stroke, vol. 46, no. 10, pp. 2943–2950, 2015. View at Publisher · View at Google Scholar · View at Scopus
- M. Hashimoto, R. Tozawa, M. Katakura et al., “Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats,” Food & Function, vol. 2, no. 7, pp. 386–394, 2011. View at Publisher · View at Google Scholar · View at Scopus
- R. J. Wurtman, M. Cansev, and I. H. Ulus, “Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides,” Journal of Nutrition, Health and Aging, vol. 13, no. 3, pp. 189–197, 2009. View at Publisher · View at Google Scholar · View at Scopus
- R. J. Wurtman, M. Cansev, T. Sakamoto, and I. H. Ulus, “Use of phosphatide precursors to promote synaptogenesis,” Annual Review of Nutrition, vol. 29, pp. 59–87, 2009. View at Publisher · View at Google Scholar · View at Scopus
- M. Igarashi, R. A. Santos, and S. Cohen-Cory, “Impact of maternal n-3 polyunsaturated fatty acid deficiency on dendritic arbor morphology and connectivity of developing Xenopus laevis central neurons in vivo,” Journal of Neuroscience, vol. 35, no. 15, pp. 6079–6092, 2015. View at Publisher · View at Google Scholar · View at Scopus
- G. K. Istaphanous, J. Howard, X. Nan et al., “Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice,” Anesthesiology, vol. 114, no. 3, pp. 578–587, 2011. View at Publisher · View at Google Scholar · View at Scopus
- J. Song, J. Park, J. H. Kim et al., “Dehydroascorbic acid attenuates ischemic brain edema and neurotoxicity in cerebral ischemia: an in vivo study,” Experimental Neurobiology, vol. 24, no. 1, pp. 41–54, 2015. View at Publisher · View at Google Scholar
- M.-O. Trépanier, K. E. Hopperton, S. K. Orr, and R. P. Bazinet, “N-3 polyunsaturated fatty acids in animal models with neuroinflammation: an update,” European Journal of Pharmacology, vol. 785, pp. 187–206, 2016. View at Publisher · View at Google Scholar · View at Scopus
- P. K. Chang, A. Khatchadourian, R. A. McKinney, and D. Maysinger, “Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology,” Journal of Neuroinflammation, vol. 12, no. 1, article 34, 2015. View at Publisher · View at Google Scholar · View at Scopus