High Mobility Group Box1 Protein Is Involved in Endoplasmic Reticulum Stress Induced by Clostridium difficile Toxin A

Figure 2

Glycyrrhizin prevents HMGB1-induced ER stress. (a) Protein expressions of IRE1α, ATF6, and PERK in CT26 cells treated with HMGB1 for the indicated time were measured by western blot. (b) rHMGB1 combined with glycyrrhizin was incubated with CT26 cells for 12 h and the protein expressions of IRE1α, ATF6, and PERK were detected by western blot analysis. Actin was used as the loading control. Data represent the mean of three independent experiments. .

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