High Mobility Group Box1 Protein Is Involved in Endoplasmic Reticulum Stress Induced by Clostridium difficile Toxin A

Figure 3

Glycyrrhizin prevents TcdA-induced cell rounding. CT26 cells were treated with glycyrrhizin and TcdA, and cell rounding rate was measured. (a) CT26 cells were pretreated with different concentrations of glycyrrhizin, followed by 10 ng/mL TcdA for 4 h, and cell rounding was quantified. (b) CT26 cells were treated with glycyrrhizin 30 min before TcdA exposure, and the rate of cell rounding was determined.

(a)

(b)