BioMed Research International / 2016 / Article / Fig 2

Research Article

A Novel Assay for the Identification of NOTCH1 PEST Domain Mutations in Chronic Lymphocytic Leukemia

Figure 2

Fragment analysis of 4 samples not harboring the mutation c.7544_7545delCT. (a) Sample with wild-type NOTCH1 revealing a single 391 bp peak. (b) T-ALL140 sample harboring the mutation c.7526_7527insT, showing a 391 bp peak and a 392 bp peak. (c) T-ALL151 sample with the complex mutation c.7458_7464delGCAGCAC, c.7457_7458insAGGCGTCTAGCCGCAT, revealing a 391 bp peak and a 400 bp peak. (d) T-ALL176 sample with the mutation c.7529_7535delTCACCCC, depicting a 391 bp peak and a 384 bp peak.