Profiles of Inflammatory Cytokines in the Vitreous Fluid from Patients with Rhegmatogenous Retinal Detachment and Their Correlations with Clinical Features
Table 1
Concentrations of intravitreal cytokines showing statistical differences.
RRD
MH
PDR
ERM
RVO
ANOVA, P
RRD-MH, P
RRD-PDR, P
IL-6
517.0 [1931.5]
77.3 [278.0]
918.0 [1703.0]
112.0 [303.75]
2116.5 [5464.0]
<0.001
0.009
0.037
IL-8
343.0 [1404.5]
94.5 [228.63]
2168.0 [3449.5]
168.0 [257.8]
4153.5 [12369.6]
<0.001
0.007
<0.001
IL-10
32.0 [47.0]
12.0 [41.4]
51.0 [60.0]
49.0 [40.0]
53.5 [86.25]
0.009
0.289
0.016
IL-12
16.0 [49.0]
12.5 [47.8]
51.0 [68.5]
53.5 [47.3]
68.5 [89.3]
0.006
0.460
0.005
IL-13
9.5 [43.5]
8.0 [34.6]
39.0 [47.0]
34.5 [44.3]
43.0 [62.1]
0.005
0.239
0.003
G-CSF
63.0 [77.0]
13.5 [50.9]
62.0 [68.5]
59.0 [55.3]
68.0 [173.4]
0.026
0.062
0.248
MCP-1
8740.0 [20034.0]
3471.3 [2930.6]
10892.0 [16580.5]
3132.0 [2318.5]
19843.0 [23562.8]
<0.001
<0.001
0.598
MIP-1β
478.0 [1202.0]
163.5 [495.8]
698.0 [921.5]
414.0 [387.0]
1170.8 [2237.6]
0.012
0.041
0.730
IP-10
3531.0 [11016.0]
390.0 [1091.8]
5858.0 [9544.5]
445.5 [2439.5]
10078.5 [22053.6]
<0.001
<0.001
0.367
PDGF
24.0 [49.0]
23.8 [43.4]
54.0 [90.5]
43.0 [65.5]
64.8 [113.9]
0.005
0.331
0.004
VEGF
355.0 [489.0]
67.0 [300.6]
4765.0 [11165.5]
260.5 [391.8]
3434.3 [20982.8]
<0.001
0.058
<0.001
Median [quartile deviation] is presented. The symbols , , and indicate statistically significant differences. : ANOVA was conducted by Kruskal-Wallis test. , : post hoc analyses were conducted by Mann-Whitney test.
