BioMed Research International / 2016 / Article / Tab 3

Research Article

Morphokinetic Characteristics and Developmental Potential of In Vitro Cultured Embryos from Natural Cycles in Patients with Poor Ovarian Response

Table 3

Comparison of timing of the events in early embryo development between normally developing embryos and embryos with cleavage irregularities.

Morphokinetic parametersNormally developing embryosEmbryos with cleavage irregularities

PB2258.5 (90.5)208.9 (88.7)0.071
PNa608.6 (214.8)556.0 (174.9)0.359
PNf1460.9 (243.1)1680.8 (526.7)0.075
VP (PNf  −  PNa)856.2 (184.8)1014.3 (310.3)0.037
ECC1 (  −  PB2)1334.1 (143,3)1610.9 (570.4)0.096
1624.2 (225.2)1813.7 (497.9)0.093
2315.4 (211.4)2472.4 (519.9)0.256
ECC2788.3 (173.7)1064.6 (263.1)0.005
Dck138.4 (42.9)324.5 (656.5)0.032
S2 ()91.5 (152.3)338.4 (361.2)0.015

Note: mean time values are in minutes, SD in parentheses. PB2: time passed from ICSI to the extrusion of the second polar body; PNa: time from ICSI to the appearance of the both pronuclei; PNf: time from ICSI to the disappearance of the pronuclei; VP: time period until the pronuclei become visible; ECC1 = −  PB2: the duration of the first cell cycle; : time from ICSI to the first frame in which two, three, and four cells are visible; ECC2 = : the duration of the second embryo cell cycle; dck1: the duration of the first cytokinesis; s2 = : the synchronization of the cell divisions between the 2- and 4-cell stages.

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