Method Based on the β-Lactamase PenPC Fluorescent Labeled for β-Lactam Antibiotic Quantification in Human Plasma

Figure 5

Use of PenPC to determine concentration of BLA in clinical samples. Plasmatic pharmacokinetics of meropenem was determined in (a) human plasma using the biosensor healthy volunteers () or (b) Sus scrofa plasma () during inflammation process: both of them at the time indicated.

(a)

(b)