Enzymatic Synthesis of Sorboyl-Polydatin Prodrug in Biomass-Derived 2-Methyltetrahydrofuran and Antiradical Activity of the Unsaturated Acylated Derivatives

Table 2

Effect of polydatin concentration on enzymatic acylation in various solvents.

Medium	(mM/h)	(mM)	/ (h^−1)
2-MeTHF	31.2	27.9	1.12
tert-Butanol	30.8	100.3	0.41
Acetone	24.7	103.2	0.24
THF	23.3	107.2	0.22

The reactions were carried out at 60°C and 200 rpm by adding various amounts of polydatin, vinyl sorbate (9 equiv.), and 100 mg CALB into 3 mL anhydrous solvent.