Infant’s DNA Methylation Age at Birth and Epigenetic Aging Accelerators

Table 2

Factors associated with positive age acceleration according to epigenetic age calculator among newborns.

Variables	Age acceleration		β	S.E.	Wald	value	OR (95% CI)
	Positive	Negative
Gender
Male	237 (56.2%)	185 (43.8%)					1.00
Female	109 (57.1%)	82 (42.9%)	0.04	0.18	0.04	0.83	1.04 (0.74–1.47)
Race
Africa-American	79 (38.7%)	125 (61.3%)					1.00
European-American	74 (46.0%)	87 (54.0%)	0.30	0.21	1.93	0.16	1.35 (0.89–2.05)
Mixed race group	12 (63.2%)	7 (36.8%)	1.00	0.50	4.03	0.04	2.71 (1.02–7.18)
Supplementation status
Placebo	24 (68.6%)	11 (31.4%)					1.00
Micronutrient	11 (52.4%)	10 (47.6%)	−0.68	0.57	1.45	0.23	0.50 (0.17–1.54)
Tobacco exposure
No	24 (66.7%)	12 (33.3%)					1.00
Yes	38 (86.4%)	6 (13.6%)	1.15	0.56	4.18	0.036	3.17 (1.05–9.56)