Research Article
Infant’s DNA Methylation Age at Birth and Epigenetic Aging Accelerators
Table 2
Factors associated with positive age acceleration according to epigenetic age calculator among newborns.
| Variables | Age acceleration | β | S.E. | Wald | value | OR (95% CI) | Positive | Negative |
| Gender | | | | | | | | Male | 237 (56.2%) | 185 (43.8%) | | | | | 1.00 | Female | 109 (57.1%) | 82 (42.9%) | 0.04 | 0.18 | 0.04 | 0.83 | 1.04 (0.74–1.47) | Race | | | | | | | | Africa-American | 79 (38.7%) | 125 (61.3%) | | | | | 1.00 | European-American | 74 (46.0%) | 87 (54.0%) | 0.30 | 0.21 | 1.93 | 0.16 | 1.35 (0.89–2.05) | Mixed race group | 12 (63.2%) | 7 (36.8%) | 1.00 | 0.50 | 4.03 | 0.04 | 2.71 (1.02–7.18) | Supplementation status | | | | | | | | Placebo | 24 (68.6%) | 11 (31.4%) | | | | | 1.00 | Micronutrient | 11 (52.4%) | 10 (47.6%) | −0.68 | 0.57 | 1.45 | 0.23 | 0.50 (0.17–1.54) | Tobacco exposure | | | | | | | | No | 24 (66.7%) | 12 (33.3%) | | | | | 1.00 | Yes | 38 (86.4%) | 6 (13.6%) | 1.15 | 0.56 | 4.18 | 0.036 | 3.17 (1.05–9.56) |
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