Positive-Unlabeled Learning for Pupylation Sites Prediction

Table 3

Independent test performance of PUL-PUP and three existing pupylation sites predictors.

Method	Threshold	Sn (%)	Sp (%)	ACC (%)	MCC	AUC
GPS-PUP	High	31.03	89.46	85.62	0.16	0.60
	Medium	34.48	85.54	82.19	0.14
	Low	41.38	76.72	74.43	0.10
iPUP	High	48.28	82.84	80.55	0.20	0.66
	Medium	51.72	76.47	74.83	0.16
	Low	55.17	72.06	70.94	0.15
pbPUP	High	17.24	88.48	83.75	0.04	0.60
	Medium	31.03	80.15	76.89	0.07
	Low	41.38	69.85	67.96	0.07
PUL-PUP	High	51.72	83.33	81.24	0.22	0.77
	Medium	65.52	76.72	75.97	0.24
	Low	68.97	72.79	72.54	0.23