Time Dependent Assessment of Morphological Changes: Leukodepleted Packed Red Blood Cells Stored in SAGM

Figure 2

Scanning electron micrographs of erythrocytes with signs of hemolysis. Micrograph (a) shows RBCs with normal biconcave shape without any sign of damage or lesions on day 0 on low magnification 2500x. However, the cells in micrographs (b and c) demonstrate a sign of hemolysis, punctate (tiny) holes in the membrane of RBCs. The micrographs (d and e) represent spherocytosis and echinocytes, respectively. The micrographs from (b) to (e) are on day 28 and on higher magnification.