Research Article

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo

Table 1

The inhibitory effect of PA on A549 implantation tumor growth in BALB/C-nu mice.

Groups (mg/kg)Number of animals survivedBody weights (g)Tumor weights (g)Inhibition rate (%)
StartEnd

Control620.38 ± 0.6624.78 ± 0.931.35 ± 0.18
5 620.7 ± 0.4424.48 ± 0.680.78 ± 0.1142.35
10 620.67 ± 0.4224.48 ± 1.430.51 ± 0.2362.50
15 620.67 ± 0.4123.38 ± 0.570.27 ± 0.1979.70

versus the vehicle control.
versus the vehicle control.