Research Article
Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo
Table 1
The inhibitory effect of PA on A549 implantation tumor growth in BALB/C-nu mice.
| Groups (mg/kg) | Number of animals survived | Body weights (g) | Tumor weights (g) | Inhibition rate (%) | Start | End |
| Control | 6 | 20.38 ± 0.66 | 24.78 ± 0.93 | 1.35 ± 0.18 | | 5 | 6 | 20.7 ± 0.44 | 24.48 ± 0.68 | 0.78 ± 0.11 | 42.35 | 10 | 6 | 20.67 ± 0.42 | 24.48 ± 1.43 | 0.51 ± 0.23 | 62.50 | 15 | 6 | 20.67 ± 0.41 | 23.38 ± 0.57 | 0.27 ± 0.19 | 79.70 |
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versus the vehicle control. versus the vehicle control.
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