The Expression of HMGB1 in Bone Marrow MSCs Is Upregulated by Hypoxia with Regulatory Effects on the Apoptosis and Adhesion

Figure 2

Effect of hypoxia on the expression of HMGB1 in BM-MSCs. Cells were exposed to hypoxic (1% O₂) or normoxic conditions for 24 h. HMGB1 at mRNA and protein levels were detected by RT-PCR ((a)-(b)) and western blotting ((c)-(d)), respectively. GAPDH and β-actin were used as the control. The data was shown as mean ± SEM (). versus normoxia.

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