The Expression of HMGB1 in Bone Marrow MSCs Is Upregulated by Hypoxia with Regulatory Effects on the Apoptosis and Adhesion

Figure 4

Effect of HMGB1 on the adhesion of BM-MSCs. (a) BM-MSCs were cultured with HMGB1 at the concentrations of 0, 10, 50, 100, and 200 ng/mL for 24 h; the representative images of BM-MSCs under phase-contrast microscopy (original magnification, ×100) were taken after the nonadherent cells were removed. (b) Quantification of adhesive cells. Data was shown as mean ± SEM (). versus non-FN group. versus “FN + 0 ng/mL HMGB1” group.

(a)

(b)