Novel Biomarker MicroRNAs for Subtyping of Acute Coronary Syndrome: A Bioinformatics Approach
Table 2
The identified miRNA biomarker candidates for acute myocardial infarction (AMI) and unstable angina (UA).
AMI
UA
miRNA ID
NOD
TF (TFP)
Pathways (percentage)
miRNA ID
NOD
TF (TFP)
Pathways (percentage)
miR-155
185
64
39 (0.21)
16 (0.46)
miR-197
151
32
24 (0.16)
2 (0.11)
miR-30e
356
32
56 (0.16)
5 (0.14)
miR-125b
109
30
20 (0.18)
4 (0.22)
miR-98
329
24
62 (0.19)
2 (0.06)
miR-590-3p
255
18
44 (0.17)
2 (0.11)
miR-23b
211
18
34 (0.16)
5 (0.14)
miR-22
158
16
32 (0.20)
0
miR-204
198
15
40 (0.20)
10 (0.29)
miR-204
198
15
40 (0.20)
2 (0.11)
miR-34a
80
14
15 (0.19)
5 (0.14)
miR-34a
80
14
15 (0.19)
6 (0.33)
let-7g
199
13
34 (0.17)
24 (0.69)
miR-486-3p
152
13
23 (0.15)
2 (0.11)
miR-576-3p
133
13
23 (0.17)
0
let-7g
199
13
34 (0.17)
13 (0.72)
miR-346
31
13
5 (0.16)
5 (0.14)
miR-346
31
13
5 (0.16)
4 (0.22)
miR-454
298
13
43 (0.14)
0
miR-340
256
11
37 (0.14)
1 (0.06)
miR-532-3p
112
12
18 (0.16)
5 (0.14)
miR-340
256
11
37 (0.14)
1 (0.06)
miR-145
55
11
11 (0.20)
8 (0.23)
miR-196b
165
11
27 (0.16)
5 (0.28)
miR-340
256
11
37 (0.14)
3 (0.09)
miR-145
55
11
11 (0.20)
3 (0.17)
miR-126
34
10
5 (0.15)
29 (0.83)
miR-324-3p
84
10
12 (0.14)
1 (0.06)
miR-621
65
10
13 (0.20)
9 (0.26)
miR-126
34
10
5 (0.15)
13 (0.72)
miR-142-3p
87
8
18 (0.21)
3 (0.09)
miR-106b
376
9
61 (0.16)
1 (0.06)
miR-31
34
7
8 (0.24)
5 (0.14)
miR-885-5p
89
9
14 (0.16)
0
miR-600
127
7
23 (0.18)
1 (0.03)
miR-132
46
8
7 (0.15)
0
miR-491-3p
119
6
21 (0.18)
0
miR-17
80
8
13 (0.16)
5 (0.28)
miR-603
149
6
32 (0.21)
2 (0.06)
miR-597
76
8
12 (0.16)
2 (0.11)
miR-93
394
6
68 (0.17)
0
miR-142-3p
87
8
18 (0.21)
1 (0.06)
miR-934
72
5
12 (0.17)
0
miR-25
260
7
40 (0.15)
0
miR-27a
50
5
15 (0.30)
3 (0.09)
miR-590-5p
112
7
23 (0.21)
0
miR-548b-3p
103
5
18 (0.17)
0
miR-324-5p
78
7
18 (0.23)
2 (0.11)
miR-101
69
4
18 (0.26)
4 (0.11)
miR-93
394
6
68 (0.17)
0
miR-128
22
4
4 (0.18)
0
miR-618
112
6
17 (0.15)
0
miR-95
69
4
10 (0.14)
0
Notes. The miRNAs were ranked based on their NOD values. miRNA IDs in bold have been reported in published studies and those with underlines were shared by both AMI and UA.
