Long Noncoding RNA-LET Suppresses Tumor Growth and EMT in Lung Adenocarcinoma

Figure 4

lncRNA-LET inhibits LAC tumor growth and cell proliferation in vivo. (a) Analysis of lncRNA-LET expression level in tumor tissues was detected by using RT-PCR. GAPDH was used as an internal control. (b) Tumor volume in lncRNA-LET overexpression group was determined by using calipers. (c) HE and immunohistochemical staining showed that lncRNA-LET overexpression inhibited the aggressive phenotype of LAC cells in vivo, as indicated by the expression of PCNA-positive cells. Data are presented as the mean ± SD of three independent experiments. .

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