Review Article

Construction Formula of Biological Age Using the Principal Component Analysis

Table 1

The basic information of study population.

ResearcherYearCountrySample sizeAge rangeHealth standard

Nakamura et al. [17]1989Japan69 malesAverage 42.6 ± 9.4 yearsHealthy population
Nakamura et al. [18]1990Japan66 females20–64 yearsHealthy population
Nakamura et al. [19]1996Japan221 males20–85 yearsHealthy population
Ueno et al. [20]2003Japan981 females (cross-sectional study)
110 females (longitudinal study)
20–80 yearsHealthy population
Nakamura and Miyao [7]2003Japan86 males31–77 yearsHealthy population, including some volunteers with hypertension, hyperlipidemia, and diabetes
Nakamura and Miyao [21]2007Japan86 males31–78 yearsHealthy population, including some volunteers with hypertension, hyperlipidemia, and diabetes
Nakamura and Miyao [22]2008Japan86 males
93 females
Males : females = 0.925 : 1
31–77 yearsHealthy population, including some volunteers with hypertension, hyperlipidemia, and diabetes
Park et al. [23]2009Korea158830–77 yearsHealthy population
Bai et al. [12]2010China392 males
460 females
Males : females = 0.852 : 1
30–98 yearsHealthy population and some volunteers with subclinical state
Jee et al. [11]2012Korea1604 males
760 females
Males : females = 2.111 : 1
30–85 yearsHealthy population and some volunteers with early state of diseases
Zhang et al. [24]2014China669 males
684 females
Males : females = 0.978 : 1
35–91 yearsHealthy population
Zhang et al. [25]2014China69 males
70 females
Males : females = 0.986 : 1
35–91 yearsHealthy population