TAMH: A Useful In Vitro Model for Assessing Hepatotoxic Mechanisms

Figure 1

Simplified mechanistic schematics of signaling pathways affected by various agents in TAMH: (a) glutathione, (b) Bcl-2 protein family, (c) Nrf2 pathway, and (d) MAPK signaling. Please refer to the text for definitions for the included abbreviations.

(a)

(b)

(c)

(d)