Diagnostic Methods of Helicobacter pylori Infection for Epidemiological Studies: Critical Importance of Indirect Test Validation

Table 4

Accuracy of several tests using histology confirmed by IHC as a gold standard.

Type of tests	Sensitivity (%)				Specificity (%)
	Dominican; Republic [13]	Bhutan [14]	Myanmar [15]	Indonesia [16]	Dominican; Republic [13]	Bhutan [14]	Myanmar [15]	Indonesia [16]
Culture	74.2	90.8	80.0	83.3	97.2	98.6	98.8	97.2
RUT	84.3	86.9	86.7	83.3	95.7	97.2	95.1	97.2
Serology	—	95.2	72.2	—	—	69.9	82.7	—
Urine test	—	—	—	50.0	—	—	—	98.6

IHC: immunohistochemistry; RUT: rapid urease test.