Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model

Figure 10

Significant difference of (a) appearing neoplasia including invasive carcinoma, high grade dysplasia, and low grade dysplasia, (b) total colitis score, and (c) colitis score of the distal segment between vitamin A-supplemented mice and vitamin A-deficient mice induced by a single preinjection of azoxymethane (7.4 mg/kg) 14 days prior to intake of 1% DSS for 7 subsequent days.

(a)

(b)

(c)