Cell Cycle Arrest and Apoptosis Induction via Modulation of Mitochondrial Integrity by Bcl-2 Family Members and Caspase Dependence in Dracaena cinnabari-Treated H400 Human Oral Squamous Cell Carcinoma

Figure 5

Changes in mitochondrial membrane potential in H400 cells treated with DC extract, fractions DCc and DCd, and subfractions DCc15 and DCd16 of D. cinnabari. H400 cells were treated at concentration of IC₅₀ for 24 hours. Untreated cells were used as negative control. Data was expressed as mean ± SEM (). Significant difference as compared to negative control () when statistical analysis was performed.