Cell Cycle Arrest and Apoptosis Induction via Modulation of Mitochondrial Integrity by Bcl-2 Family Members and Caspase Dependence in Dracaena cinnabari-Treated H400 Human Oral Squamous Cell Carcinoma

Table 1

Cytotoxicity (IC₅₀) of D. cinnabari crude extract and Cisplatin on OSCC cell lines.

Cell lines	IC50  ± SEM (μg/mL)
	D. cinnabari extract	Cisplatin
H400	5.9 ± 0.35	4.1 ± 0.55
H103	6.0 ± 0.08	0.8 ± 0.12
H376	7.2 ± 0.16	0.6 ± 0.03
H357	9.0 ± 1.63	2.0 ± 0.12
H314	17.4 ± 1.56	7.0 ± 0.58
H413	19.2 ± 1.47	2.0 ± 0.26

Data are presented as mean of triplicate values ± SEM. IC₅₀ values ≤20 μg/mL are considered cytotoxic.