Research Article

The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils

Table 2

Histopathological response seen in gerbil gastric corpus in response to Helicobacter pylori infection and treatment with either antibiotics therapy or 18β-Glycyrrhetinic acid (GRA).

GroupsTreatmentsCorpus
Infiltration of neutrophilsInfiltration of mononuclear cellsHyperplasiaPeptic ulcer

AUninfected0.0 ± 0.00.0 ± 0.00.0 ± 0.00.0 ± 0.0
BH. pylori infection1.6 ± 0.11.3 ± 0.11.5 ± 0.11.8 ± 0.3
CAntibiotics0.9 ± 0.20.7 ± 0.20.6 ± 0.30.8 ± 0.2
DGRA0.9 ± 0.20.8 ± 0.20.7 ± 0.20.9 ± 0.2

, compared with Group B. Values for results are expressed as means ± SD.