Research Article

The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils

Table 3

Histopathological response seen in gerbil gastric antrum in response to Helicobacter pylori infection and treatment with either antibiotics therapy or 18β-Glycyrrhetinic acid (GRA).

GroupsTreatmentsAntrum
Infiltration of neutrophilsInfiltration of mononuclear cellsHyperplasiaPeptic ulcer

AUninfected0.0 ± 0.00.0 ± 0.00.0 ± 0.00.0 ± 0.0
BH. pylori infection2.9 ± 0.33.0 ± 0.22.2 ± 0.32.1 ± 0.3
CAntibiotics2.0 ± 0.41.6 ± 0.11.6 ± 0.31.0 ± 0.0
DGRA2.2 ± 0.42.0 ± 0.21.5 ± 0.11.2 ± 0.3

, compared with Group B. Values for results are expressed as means ± SD.