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BioMed Research International
Volume 2016, Article ID 5029797, 10 pages
http://dx.doi.org/10.1155/2016/5029797
Research Article

7,8-DHF Treatment Induces Cyr61 Expression to Suppress Hypoxia Induced ER Stress in HK-2 Cells

1Department of Nephrology, Affiliated Hospital of Qingdao University, Qingdao 266003, China
2Key Laboratory, Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Qingdao University, Qingdao 266003, China

Received 14 July 2016; Accepted 21 November 2016

Academic Editor: Decheng Yang

Copyright © 2016 Rui Ma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1: Expression of TrkB in HK-2 cells.

Figure S2: PI3K/AKT inhibitor decreased the protein levels of p-AKT and Cyr61. Data were presented as the mean ± SD (n = 5 per group). *p<0.05 and **p<0.01 versus hypoxia alone (DMSO) group. &p<0.05 versus hypoxia + 7,8-DHF(100uM) group.

  1. Supplementary Material