Clinical Study
Efficacy and Safety of LASIK Combined with Accelerated Corneal Collagen Cross-Linking for Myopia: Six-Month Study
Table 1
The differences in parameters before operation and 1, 3, and 6 months after operation.
| Parameters | Before operation | After operation | value | value | 1 month | 3 months | 6 months |
| UCVA (logMAR) | | | | | | 0.734 | LASIK-ACXL | 1.06 ± 0.20 | −0.06 ± 0.08 | −0.14 ± 0.06 | −0.17 ± 0.04 | <0.001 | | LASIK-only | 1.00 ± 0.21 | −0.12 ± 0.05 | −0.15 ± 0.07 | −0.18 ± 0.04 | <0.001 | | CDVA (logMAR) | | | | | | 0.176 | LASIK-ACXL | −0.17 ± 0.06 | −0.14 ± 0.06 | −0.17 ± 0.07 | −0.18 ± 0.03 | 0.134 | | LASIK-only | −0.18 ± 0.06 | −0.17 ± 0.04 | −0.17 ± 0.04 | −0.18 ± 0.03 | 0.007 | | Sphere (D) | | | | | | 0.063 | LASIK-ACXL | −6.17 ± 1.89 | 0.15 ± 0.45 | 0.20 ± 0.45 | 0.18 ± 0.18 | <0.001 | | LASIK-only | −5.61 ± 2.81 | 0.10 ± 0.27 | 0.13 ± 0.52 | 0.14 ± 0.16 | <0.001 | | Cylinder (D) | | | | | | 0.582 | LASIK-ACXL | −0.80 ± 1.00 | −0.03 ± 0.22 | −0.05 ± 0.19 | −0.09 ± 0.24 | <0.001 | | LASIK-only | −0.65 ± 0.99 | −0.02 ± 0.34 | −0.03 ± 0.27 | −0.04 ± 0.18 | <0.001 | | MRSE (D) | | | | | | 0.313 | LASIK-ACXL | −6.54 ± 2.03 | 0.10 ± 0.58 | −0.10 ± 0.43 | −0.05 ± 0.33 | <0.001 | | LASIK-only | −5.95 ± 2.33 | −0.05 ± 0.69 | −0.05 ± 0.44 | −0.02 ± 0.42 | <0.001 | | Mean K (D) | | | | | | 0.927 | LASIK-ACXL | 43.98 ± 1.69 | 39.45 ± 1.54 | 39.59 ± 1.68 | 39.54 ± 1.67 | <0.001 | | LASIK-only | 43.66 ± 1.78 | 39.48 ± 1.84 | 39.65 ± 2.01 | 39.60 ± 2.11 | <0.001 | | TCT (µm) | | | | | | 0.844 | LASIK-ACXL | 524.52 ± 25.95 | 449.76 ± 41.56 | 440.19 ± 29.35 | 438.42 ± 27.40 | <0.001 | | LASIK-only | 525.56 ± 25.99 | 440.64 ± 33.65 | 435.14 ± 26.99 | 437.38 ± 24.37 | <0.001 | | ECD (cell/mm2) | | | | | | 0.869 | LASIK-ACXL | 2732.38 ± 110.37 | 2809.64 ± 145.88 | 2712.49 ± 128.34 | 2698.17 ± 137.09 | 0.295 | | LASIK-only | 2726.75 ± 107.45 | 2763.45 ± 129.76 | 2796.57 ± 139.18 | 2702.96 ± 136.95 | 0.320 | |
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value: compared between preoperation and 6 months after operation. value: compared between two groups at 6 months after operation. ACXL, accelerated corneal collagen cross-linking; UDVA, uncorrected distance visual acuity; CDVA, corrected distance visual acuity; MRSE, manifest refraction spherical equivalent; , keratometry; TCT, thinnest corneal thickness; ECD, endothelial cell density.
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