The Association between VDR Gene Polymorphisms and Diabetic Retinopathy Susceptibility: A Systematic Review and Meta-Analysis
Table 1
Characteristics of 7 studies included in this systematic review and meta-analysis.
Author
Publishing year
Population
Ethnicity
Genotyping method
Type of diabetes
Case/control
(case/control)
% of males (case/control)
Mean age (case/control)
Duration of diabetes (case/control)
HbA1c (case/control)
Zhong et al.
2015
Chinese
Asian
PCR-RFLP
DM2
DR/NDR
94/110
46.8/46.4
58.71/57.08
10.0/5.0
9.2/8.35
Hou et al.
2015
Chinese
Asian
PCR-RFLP
DM2
DR/NDR
162/92
48.4/48.9
Not available
Not available
Not available
Wu et al.
2010
Mongolian
Asian
PCR-RFLP
DM2
DR/NC
62/68
51.6/44.1
53.8/51.6
Not available
Not available
Bućan et al.
2009
Croatian
Caucasian
PCR-RFLP
DM1
DR/NDR
19/28
Not available
Not available
Not available
Not available
Cyganek et al.
2006
Polish
Caucasian
PCR-RFLP
DM2
DR/NDR
85/182
42.4/46.7
Not available
14.6/9.7
8.4/7.5
Taverna et al.
2005
French
Caucasian
PCR-RFLP
DM1
SDR/NSDR
126/128
46.8/53.1
40.7/42.9
25.5/25.1
9.02/7.88
Taverna et al.
2002
French
Caucasian
PCR-RFLP
DM1
SDR/NSDR
101/99
44.6/58.6
Not available
30.0/25.2
8.9/8.3
DM1: type 1 diabetes; DM2: type 2 diabetes. DR: diabetic retinopathy; NDR: diabetes without retinopathy. SDR: severe diabetic retinopathy (severe nonproliferative DR or proliferative DR); NSDR: nonsevere diabetic retinopathy (no DR or minimal nonproliferative DR). NC: normal control.
